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WHAT IS NMN?

Hearing about NMN for the First Time?

Curious about NMN? Allow us to introduce you to this groundbreaking compound. Learn what NMN is, how it works, and why it's creating buzz in the world of longevity and wellness.

NMN, which is short for nicotinamide mononucleotide, is a substance generated naturally in your body from vitamin B3 and plays a vital role in the activity of the cells. NMN is a precursor of NAD (nicotinamide dinucleotide), a coenzyme that exists in the cells of all organisms. NMN is created in your body from vitamin B3 naturally, but your body gradually loses its ability to generate it as you get older. In 2011, a world authority on NMN, Professor Shin-ichiro Imai (Washington University in St. Louis, Department of Behavioral Biology, School of Medicine, Missouri, US), reported its existence and effects.

What foods are rich in NMN?

NMN is contained in vegetables like edamame, broccoli or avocado, fruits and seeds, among others. However, with age we lose our ability to create NMN, and the amount of NMN we can receive from our diet is just not enough. If you want to take 150 mg of NMN, you would need to ingest 12000 edamame beans or 2400 heads of broccoli, which is obviously far beyond what your stomach can take, so the best you can do is turning to NMN supplements and products.

Applications of NMN

NMN can have anti-aging effects. If it acts on certain genes, it could prevent aging, and rejuvenate. These genes are the sirtuins, the longevity genes, and they exist all over your body. We all have them, and sirtuin genes are considered to prevent aging and prolong lifespan.

The results of NMN research, which is ongoing at a global scale, have attracted the attention of the media because this is a next-generation component that could rejuvenate us from a genetic level as it provides energy to the sirtuin genes.

What’s the effective way to take NMN?

The world-leading authority on NMN, Professor Shin-ichiro Imai thinks it is reasonable to take 300-500 mg of NMN per day. He says he could verify the effects with an intake of 250 mg per day in his first clinical trial carried out at Washington University, but this does not necessarily mean effects could be obtained with a higher dose. Also, NAD fluctuates to suit our circadian rhythm (our body clock), so according to Professor Imai, it is a good idea to take NMN capsules when we are the most active, which is usually some time between early morning to midday.

What are the rejuvenating sirtuin genes that NMN activates?

We can expect anti-aging effects from NMN. The “rusting of the body” caused by active oxygen is one of the causes of aging. Your body produces active oxygen when you breathe. Active oxygen causes the oxidation of your body and is one of the factors behind the proliferation of wrinkles on your skin and bad cholesterol.
If certain genes are activated, we could prevent aging, and rejuvenate. These genes are the sirtuins, the longevity genes, and they exist all over your body. We all have them, and sirtuins are considered to prevent aging and prolong lifespan.NMN is in the spotlight because it is a next-generation component that could rejuvenate us from a genetic level as it provides energy to the sirtuin genes.

Optical enantiomers (α-NMN and β-NMN)

NMN exists with two different molecular structures: α-NMN and β-NMN.
These two structures have exactly the same number and type of atoms, but the connections between them point in different directions. These structures are called “optical enantiomers.” You can see the differences between α-NMN and β-NMN in the images below.

The NMN that we need is β-NMN, which is naturally generated in our bodies. The other NMN, α-NMN, is something we don’t need and something not produced in us.
However, NMN manufactured by chemical synthesis for the sake of cost reduction will most probably end up being a mixture of α-NMN and β-NMN. Products that contain full β-NMN must be manufactured according to an extremely precise process, and that’s exactly what Mirai Lab is offering you: high-quality NMN supplements with the only NMN you should care about, β-NMN.

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World-leading authority on NMN Professor Shin-Ichiro Imai blows the whistle on the pandemonium of NMN capsules available on the market and warns that the only products whose safety on humans has been proven are from Japan’s Mirailab Bioscience.

Mirailab brings you NMN products with almost no impurities, full β-NMN (never α-NMN) with an absolute purity over 99.8%, unmatched by any other company.

In addition, we were the first in the world to conduct human clinical research, and since we have the only in-house research laboratory specialized in NMN in Japan, we earned ourselves a reputation as pioneers of NMN bio-venture research. If you want the real thing, take Mirai Lab’s academia-quality NMN supplements.